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The influence of CdCl 2 , used at 1, 10 and 100 μM concentration, and ZnCl 2 at 1, 10 and 100 μM concentration on the production of interferon (IFN) and tumor necrosis factor (TNF) in bovine aorta endothelial cells (BAECs) was examined. BAECs were treated with cadmium ions or zinc ions alone or together with cytokine inducers: Newcastle disease virus (NDV) and lipopolysaccharide (LPS)...
The prevention of apoptosis by Zn 2+ is a well-known phenomenon. Both in in vitro and in vivo Zn 2+ supplementation prevents apoptosis induced by a variety of agents, among them by cadmium ions. The target for protective action of Zn ions on cell apoptosis is still unknown. In this paper we have evaluated the effect of in vitro ZnCl 2 supplementation at a concentration...
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