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Scope: Tetrahydrocurcumin (THC), a major metabolite of curcumin (CUR), has been demonstrated to be anti‐cancerogenic and anti‐angiogenic and prevents type II diabetes. In this present study, we investigated the chemopreventive effects and underlying molecular mechanisms of dietary administration of CUR and THC in azoxymethane (AOM)‐induced colon carcinogenesis in mice.
Methods and results: All mice...
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