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An amperometric sensor for the detection of cyanide integrated in a flow injection analysis (FIA) system is presented. The specificity of the sensor for cyanide is achieved by a reaction cascade involving two enzymes, cyanidase (EC 3.5.5.1) and formate dehydrogenase (FDH, EC 1.2.1.2). The limit of detection (LOD) and the limit of quantification (LOQ) were determined to be in the low micromolar range...
In environmental analysis, cyanide and heavy metals play an important role, because these substances are highly toxic for biological systems. They can lead to chronic and acute diseases. Due to the chemical properties of cyanide it is frequently used for industrial processes such as extraction of silver and gold. Heavy metals can be found as trace elements in nature and are often applied in industries...
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