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Wingless‐related integration site (Wnt) signaling is one of the main oncogenic pathways in different malignancies. Therefore, targeting this pathway has been considered an exciting strategy in cancer treatment. Porcn is among the central enzymes in this pathway that has recently been considered for cancer‐targeted therapy. As a membrane‐bound O‐acyltransferase, Porcn plays a critical role in wnt ligand...
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