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Ions derived from nano-electrospray ionization (nano-ESI) of α-synuclein, a 14.5kDa, 140 amino acid residue protein that is a major component of the Lewy bodies associated with Parkinson's disease, have been subjected to ion trap and beam-type collisional activation. The former samples products from fragmentation at rates generally lower than 100s −1 whereas the latter samples products from...
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