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Integration of dual‐barrel membrane patch‐ion channel probes (MP‐ICPs) to scanning ion conductance microscopy (SICM) holds promise of providing a revolutionized approach of spatially resolved chemical sensing. A series of experiments are performed to further the understanding of the system and to answer some fundamental questions, in preparation for future developments of this approach. First, MP‐ICPs...
In this paper, we proposed a calibration strategy utilizing reference sensor for bio-detection based on GMR sensor. With this calibration strategy, temperature drift effect can be cancelled by about 85%, and the carrier signal can be reduced by 26dB enabling a dynamic range adjustment for quantization. A 90% reduction of front-end common mode noise and error, and a sensitivity of 50ppm or 600 200nm-diameter...
This paper presents a high sensitivity oscillator-based magneto-sensitive biosensor. A fully integrated on-chip low noise low-dropout voltage regulator (LDO) with a low temperature coefficient double-stacked diode bandgap is introduced to suppress the environmental variations, e.g. voltage vibration, temperature drift. As an implementation example, a biosensor cell is designed in a standard 180-nm...
This letter presents a high sensitivity oscillator-based magneto-sensitive biosensor. To suppress the environmental variations, e.g., voltage vibration, temperature drift, and lower the noise floor, an in-situ switched capacitor (ISSC) based calibration scheme is proposed with little cost on on-chip area and complexity. As an implementation example, a biosensor cell is designed in a standard 180-nm...
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