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Nanocatalytic medicine has emerged as a promising method for the specific cancer therapy by mediating the interaction between tumor microenvironment biomarkers and nanoagents. However, the produced antitumor cell killing molecules, such as reactive oxygen species (ROS), by catalysis are insufficient to inhibit tumor growth. Herein, a novel kind of polyvinyl pyrrolidone modified multifunctional iron...
In article number 2007991, Yu Luo, Hangrong Chen, and co‐workers report a novel kind of polyvinyl pyrrolidone modified multifunctional iron sulfide nanoparticles (Fe1−xS‐PVP NPs), which can in situ generate highly toxic hydroxyl radicals under a tumor environment and simultaneously produce H2S gas to suppress the activity of the enzyme cytochrome c oxidase in cancer cells. The external stimulation...
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