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Applications of solid lipid nanoparticles (SLNs) in drug delivery and the encapsulation of bioactive, lipophilic compounds have been hindered by the tendency of SLN suspensions to undergo uncontrolled aggregation due to polymorphic transformation of the lipid crystals. Second generation lipid nanoparticle systems have been developed by mixing liquid lipid with solid lipid to form more stable nanostructured...
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