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An X-ray contrast agent precursor based on C 60 has been designed, synthesized, and characterized. The compound is the monoadduct of a malonodiamide containing six iodine atoms and eight acetal-protected alcohols with multiple hindered rotations at ambient temperature.
The most water-soluble (>240 mg C 60 mL -1 ) fullerene derivatives to date, the new malonodiserinolamide fullerenes C 60 [C(COSer) 2 ] n (n=4, 5, 6, Ser=2-amino-1,3-propanediol), have been synthesized and characterized. The compounds were designed to provide maximum water solubility and biological compatibility. The facile synthesis is based...
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