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Abstract.Eleven infusion solutions containing carboplatin (10mg/ml) stored for 5 to 78 months at room temperature were investigated for the content of carboplatin and the profile of decomposition products by means of atomic absorption spectrophotometry (AAS) and high performance liquid chromatography (HPLC). Carboplatin loss was between 3.09% and 7.28%. Carboplatin degradation was exponential and...
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