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BACKGROUNDThe current head and neck squamous cell carcinoma (HNSCC) staging system may not capture the full prognostic implications of regional lymph node involvement. This study investigated the impact of the level of lymph node metastasis (LNM) on survival.
METHODSThe Surveillance, Epidemiology, and End Results registry was queried for oral cavity (OC), oropharynx (OP), larynx (LAR), and hypopharynx...
BACKGROUNDWeekly or daily cisplatin and 5‐fluorouracil (5‐FU)‐based chemoradiation was evaluated for patients with locally advanced squamous cell carcinoma (SCC) of the anal canal treated at a single institution over a 20‐year period.
METHODSA retrospective, single‐institution analysis was conducted of patients receiving concurrent 5‐FU/cisplatin and radiotherapy for locally advanced SCC from 1989...
BACKGROUND:Cancer registries use algorithms to process cause of death (COD) data from death certificates, but uncertainties remain regarding the accuracy and utility of those data in calculating cancer‐specific survival (CSS). Because it is impractical to reconfirm the COD through meticulous review of the primary medical records, the observed cancer deaths could be compared with the number of attributed...
BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage‐specific survival outcomes in patients with stage III and high‐risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence‐based guidelines for organ‐specific cancer care, including care of patients with colon cancer.
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BACKGROUND:Secondary lymphedema is a debilitating, chronic, progressive condition that commonly occurs after the treatment of breast cancer. The purpose of the current study was to perform a systematic review and meta‐analysis of the oncology‐related literature excluding breast cancer to derive estimates of lymphedema incidence and to identify potential risk factors among various malignancies.
METHODS:The...
BACKGROUND:Neuroendocrine carcinoma (NEC) of the breast, a pathologic entity newly defined in the 2003 World Health Organization classification of tumors, is a rare type of tumor that is not well recognized or studied. The purpose of this first case‐controlled study is to reveal the clinicopathologic features, therapeutic response, and outcomes of patients with NEC of the breast.
METHODS:Seventy‐four...
BACKGROUND:Conditional survival (CS) has emerged as a clinically relevant measure of prognosis for cancer survivors. The objective of this analysis was to provide melanoma‐specific CS estimates to help clinicians promote more informed patient decision making.
METHODS:Patients with melanoma and at least 5 years of follow‐up were identified from the Surveillance Epidemiology and End Results registry...
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