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The possibility for determination of the water content in pharmaceutical samples by near-infrared (NIR) spectroscopy has been more widely investigated in the past few years. However, many studies claim that changes in sample composition will require the establishment of a new method. The aim of this study was several fold: firstly to investigate validation aspects of water content determination in...
The quality assurance of the product during the whole development and manufacturing cycle of pharmaceuticals through increased level of process understanding is the main aspect to be considered within process analytical technology (PAT). Therefore, development of new tools using, e.g., multivariate methods for quality control in different steps of manufacturing process are of great importance. In...
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