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Sulphated hyaluronic acids having a sulphation degree of 3.5 per disaccharide unit, HyalS 3.5 , were prepared with different molecular weights corresponding to 21 10 3 , 320 10 3 and 3500 10 3 . The thrombin inhibition in plasma and in the presence of purified molecules, i.e. fibrinogen, antithrombin III (AT III) and heparin cofactor II (HC II),...
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