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Mammalian cell-enclosing capsules have been investigated as devices for bioproduction, cell therapy and stem cell research. In this study, carboxymethylcellulose (CMC) with phenol moieties (CMC-Ph), synthesized through the conjugation reaction of CMC and tyramine, was investigated as a material for these types of devices. Subsieve-size capsules of less than 100 μm in diameter were prepared by extruding...
Immunoisolatability, mechanical stability and biocompatibility of cell-enclosing microcapsules are controlled by the formation of external polyelectrolyte complex membranes. The present study aimed to develop cell-enclosing subsieve-size capsules of less than 100μm in diameter for controlling these properties. We investigated the use of anionic polysaccharide alginate combined with thermosensitive...
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