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Taxanes are potent antimitotic agents that have demonstrated efficacy in a wide range of malignancies. Due to their poor water-solubility, these cytostatic drugs were first formulated with low molecular weight surfactants, e.g. Cremophor ® EL (CrEL) and Tween 80 ® (polysorbate 80), which are known to exhibit serious adverse effects in humans. In recent years, there has been growing...
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