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Bone marrow–derived mesenchymal stem cells (BMSCs) undergo hypoxia-induced apoptosis when cells are transplanted from a normoxic to a hypoxic microenvironment in vivo. The effect of the osteogenic microenvironment on BMSCs under hypoxic conditions has not yet been revealed.In the current study, we investigated the effects on BMSCs of hypoxia and osteogenic induction (OI) individually and in combination...
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