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Here we report on an ultra‐sensitive colorimetric sensing platform that takes advantage of both the strong amplification power of rolling circle amplification (RCA) and the high efficiency of a simple urease‐mediated litmus test. The presence of a target triggers the RCA reaction, and urease‐labelled DNA can hybridize to the biotinylated RCA products and be immobilized onto streptavidin‐coated magnetic...
Here we report on an ultra‐sensitive colorimetric sensing platform that takes advantage of both the strong amplification power of rolling circle amplification (RCA) and the high efficiency of a simple urease‐mediated litmus test. The presence of a target triggers the RCA reaction, and urease‐labelled DNA can hybridize to the biotinylated RCA products and be immobilized onto streptavidin‐coated magnetic...
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