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Key points
Sickle cell disease (SCD) results in cardiopulmonary dysfunction, which may be exacerbated by prolonged exposure to environmental hypoxia.
It is currently unknown whether exposure to mild and moderate altitude exacerbates SCD associated cardiopulmonary and systemic complications.
Three months of exposure to mild (1609 m) and moderate (2438 m) altitude increased rates of haemolysis and...
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