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This research was aim to develop novel cyclodextrin/chitosan (CD/CS) nanocarriers for insoluble drug delivery through the mild ionic gelation method previously developed by our lab. A series of different β-cyclodextrin (β-CD) derivatives were incorporated into CS nanoparticles including hydroxypropyl-β-cyclodextrin (HP-β-CD), sulphobutylether-β-cyclodextrin (SB-β-CD), and 2,6-di-O-methy-β-cyclodextrin...
Keggin type heteropolyacids was found to be an efficient and reusable catalyst for the synthesis of biologically active quinoxaline derivatives from the condensation of 1,2-diamine with 1,2-dicarbonyl compounds in excellent yields in water. This method provides a new and efficient protocol in terms of small quantity of catalyst, a wide scope of substrates, and simple work-up procedure.
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