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Endoplasmic reticulum (ER) resident proteins may be maintained in the ER by retention, where the leak into post‐ER compartments is absent or slow, or retrieval, where a significant leak is countered by retrieval from post‐ER compartments. Here the targeting of the C‐terminally anchored protein ER‐resident protein, cytochrome b5a (cytb5a), considered to be maintained in the ER mainly by the process...
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