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We deleted the two C-terminal residues of the scorpion toxin BmTx3, a peptidyl inhibitor of a transient A-type K + current in striatum neurons in culture, to assess their contribution to receptor recognition. The sBmTX3-delYP analog was shown to have a native-like structure in one-dimensional 1 H-nuclear magnetic resonance (NMR) spectroscopy. We found that sBmTX3-delYP bound to its...
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