The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
We carried out docking and molecular dynamics simulations on ABT‐737 and obatoclax, which are inhibitors of the Bcl‐2 family of proteins. We modeled the binding mode of ABT‐737 with Bcl‐xL, Bcl‐2, and Mcl‐1 and examined their dynamical behavior. We found that the binding of the chlorobiphenyl end of ABT‐737 was quite stable across all three proteins. However, the phenylpiperazine linker group was...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.