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Polyamidoamine (PAMAM) dendrimer/DNA complexes encapsulated in a water soluble polymer, poly-α,β-[N-(2-hydroxyethyl)-l-aspartamide], were supported on a cholic acid functionalized star poly(dl-lactide) film with a fast degradation rate to mediate localized gene delivery. The in vitro gene transfections of two types of cells, HEK293 and NIH3T3, were investigated. The expressions of pGL3-Luc and pEGFP-C1...
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