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Abstract.A high performance liquid chromatographic (HPLC) method to study the stability of carboplatin (cis-diammine(1,1-cyclobutanedicarboxylato)-platinum(II)) in commercial products was developed and validated according to the recommendations of the International Harmonization Conference [1]. For analytical applications a Nucleosil-100-5 C18 column and an isocratic system of CH3OH/(0.001N H2SO4/0...
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