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The tumor necrosis factor (TNF) antagonist etanercept is an antirheumatic agent which was approved by Japanese regulatory authorities in January 2005. In Japan, the cost-effectiveness of this therapy for patients with rheumatoid arthritis (RA) has not previously been evaluated. This study models the cost-utility of etanercept in comparison with standard therapy with disease-modifying antirheumatic...
An examination of the localization and distribution of -endorphin and opioid receptors in patients with rheumatoid arthritis (RA) and osteoarthritis (OA). Immunohistochemical staining, reverse transcription polymerase chain reaction (RTPCR) analysis, and in situ hybridization were performed using synovial tissues obtained from RA and OA patients. Immunohistochemical staining showed that -endorphin...
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