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Omega‐6 (n‐6) arachidonic acid (AA) and its pro‐inflammatory metabolites, including prostaglandin E2 (PGE2), are known to promote tumorigenesis. Delta‐6 desaturase (D6D) is the rate‐limiting enzyme for converting n‐6 linoleic acid (LA) to AA. Our objective was to determine if AA synthesis, specifically D6D activity, and PGE2 levels are increased in cancerous breast tissue, and whether these variables...
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