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A highly efficient cap‐exchange approach for preparing compact, dense polyvalent mannose‐capped quantum dots (QDs) has been developed. The resulting QDs have been successfully used to probe multivalent interactions of HIV/Ebola receptors DC‐SIGN and DC‐SIGNR (collectively termed as DC‐SIGN/R) using a sensitive, ratiometric Förster resonance energy transfer (FRET) assay. The QD probes specifically...
Vier Bienen ……, welche die vier Domänen für die Kohlenhydraterkennung (CDRs) im HIV/Ebola‐Rezeptor DC‐SIGN darstellen, suchen nach “Lollis”, d. h. kohlenhydratkonjugierten Quantenpunkten (QDs). Um erfolgreich zu sein, müssen sie dem richtigen “SIGN” folgen, in dieselbe Richtung fliegen und zusammenarbeiten. Y. Guo, D. Zhou et al. berichten in der Zuschrift auf S. 4816 ff. über die simultane Konjugation...
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