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This chapter describes the basic physics underlying the newly emerging technique of electrospray deposition (ESD) as applied to biological macromolecules. Fabrication of protein films and microarrays are considered as the most important applications of this technology. All the major stages in the ESD process (solution electrification, formation of a cloud of charged microdroplets, transformation of...
A simple method for manufacturing biological nano-aerosols is described. It is based on gas-phase neutralization of a cloud of highly charged electrospray-generated particles or macromolecular ions with a cloud of oppositely charged electrospray products, e.g., ions of a volatile solvent. It was demonstrated that the electrosprayed products became neutralized within a few seconds, forming a stable...
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