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Bilayer lipid membranes (BLMs) embedded with ionophores are described that selectively induce membrane permeability changes upon binding analyte ions at the membrane/aqueous solution interfaces. A variety of ionophores for various metal ions, such as valinomycin, a lipophilic derivative of 2,2'-bipyridyl, ETH 4120 and dihexadecyl phosphate, were directly incorporated into planar BLMs formed by two...
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