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To compare seed loss and dosimetric parameters between stranded and loose 125 I seeds (LS) for prostate brachytherapy.Sixty-four patients with 1997 American Joint Commission on Cancer (AJCC) clinical stage T1c or T2a prostate carcinoma were prospectively randomized to brachytherapy (144Gy) with RAPID Strand 125 I seeds (RS) vs. LS (Oncura, Plymouth Meeting, PA) The treatment plan for...
We assess risks, toxicity and side effects of multiple and repeat in situ suicide gene therapy in patients with localized prostate cancer.The study population comprised patients with localized prostate cancer receiving multiple and/or repeat intraprostatic injections of a replication deficient adenovirus containing the herpes simplex virus thymidine kinase (HSV-tk) gene. Intravenous ganciclovir or...
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