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GUSTO I data on thrombolytic treated pts on IV heparin demonstrated a clear association of higher aPTT's (75 sec) and death, bleeding and re-MI. AHCPR guidelines recommend a 70 U/kg IV Bolus (B) and a 15 U/kg/hr infusion. We evaluated aPTT's of 5571 pts in GUSTO IIb who received 5000U of heparin IVB and 1000 U/hr with (n = 1543) or without (n = 4028) thrombolytics and divided them into sub-therapeutic...
Atrial fibrillation (AF) is the most common arrhythmia seen after CABG occurring in 25%-40% of pts. Recently minimally invasive direct coronary artery bypass surgery (midCAB) has been explored as an alternative to the traditional CABG. Because of differences in surgical approach and post-op recovery among the 2 procedures, we looked at the incidence of AF in pts undergoing midCAB and CABG. Forty-two...
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