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Mammalian taste system can detect and distinguish various taste signals presented by different tastants using various kinds of taste bud cells. This study described a novel bioelectronic sensor in which taste bud cells were used as biotransducer for detecting bitter signals to investigate taste signal transduction. Using a light-addressable potentiometric sensor (LAPS) as sensing chip to monitor both...
This paper describes a polycystic kidney disease-like (PKD) channel-based biosensor for the research of taste transduction by extracellular recording using a micro electrode array (MEA). PKD channels, which were recently proposed as candidates for sour sensation, are heterologously expressed in human embryo kidney-293 cells and coupled with MEA chips to serve as sensitive elements. MEA chips are used...
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