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Objective
Studies have consistently shown that African American individuals lose less weight in response to behavioral interventions, but the mechanisms leading to this result have been understudied.
Methods
Data were derived from the PROmoting Successful Weight Loss in Primary CarE in Louisiana (PROPEL) study, which was a cluster‐randomized, two‐arm trial conducted in primary care clinics. In...
Objective
This study tested whether initial weight change (WC), self‐weighing, and adherence to the expected WC trajectory predict longer‐term WC in an underserved primary‐care population with obesity.
Methods
Data from the intervention group (n = 452; 88% women; 74% Black; BMI 37.3 kg/m2 [SD: 4.6]) of the Promoting Successful Weight Loss in Primary Care in Louisiana trial were analyzed. Initial...
Objective
The aim of this study was to test the hypothesis that ephedrine + caffeine (EC) reduces the fall in resting energy expenditure (REE) following bariatric surgery.
Methods
This 32‐week, randomized, double‐blinded, placebo‐controlled trial included 142 patients who underwent Roux‐en‐Y gastric bypass (RYGB) or sleeve gastrectomy (SG) surgery. Participants were randomized to either EC or placebo...
Objective
The aim of this study was to report the results of five weight‐loss interventions in primary care settings in underserved patients and to compare the level of pragmatism across the interventions using the Pragmatic Explanatory Continuum Indicator Summary (PRECIS‐2) tool.
Methods
Data from 54 primary care clinics (2,210 patients) were pooled from the Promoting Successful Weight Loss in...
Objective
Naringenin, a citrus flavonoid, prevents diet‐induced weight gain and improves glucose and lipid metabolism in rodents. There is evidence that naringenin activates brown fat and increases energy expenditure in mice, but little is known about its effects in humans. The goal of this study was to examine the effects of naringenin on energy expenditure in adipose tissue.
Methods
Human white...
Objective
Given the disease burden and economic costs of obesity in the United States, scalable approaches to weight loss and weight management are needed. This study evaluated self‐reported weight‐loss outcomes associated with a commercial intensive lifestyle intervention marketed to employers and delivered electronically to employees.
Methods
Data were collected for participants who enrolled...
Objective
The goal of this study was to determine attitudes and practices of physicians in training with respect to the evaluation and treatment of obesity.
Methods
Resident‐generated admission and discharge notes of all 1,765 general medicine hospital admissions during 4 nonconsecutive months were analyzed, and any references to weight, obesity, BMI, adiposity, and body fat were identified. The...
Objective
Multiple factors contribute to the rising rates of obesity and to difficulties in weight reduction that exist in the worldwide population. Caloric intake via sugar‐sweetened beverages may be influential. This study tested the hypothesis that liquid sucrose intake promotes obesity by increasing serum insulin levels and tissue lipid accumulation.
Methods
C57BL/6J mice were given 30% sucrose...
Objective
Dietary methionine restriction (MR) improves biomarkers of metabolic health, in part through coordinated increases in energy intake and energy expenditure (EE). Some metabolic benefits of dietary MR are secondary to its effects on energy balance, so this study's purpose was to examine how age at initiation of MR influences its effects on energy balance and body composition.
Methods
Energy...
Objective
To examine the joint association of birth weight and physical activity/sedentary time with childhood obesity in 12 countries.
Methods
A cross‐sectional study of 5,088 children aged 9 to 11 years was conducted. Birth weight was recalled by parents or guardians. Moderate‐to‐vigorous physical activity (MVPA) and sedentary behavior were objectively measured using accelerometry.
Results...
Objective
The aim was to assess associations between lifestyle behaviors and obesity in a multinational study of children from 12 countries representing a wide range of human development.
Methods
The sample included 6,025 children 9–11 years of age. Behavioral risk factors included nocturnal sleep duration, moderate to vigorous physical activity (MVPA), television viewing (TV time), and healthy...
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