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To evaluate the pharmacokinetics of amitriptyline and its active metabolite nortriptyline after intravenous (IV) and oral amitriptyline administration in healthy dogs. Prospective randomized experiment. Five healthy Greyhound dogs (three males and two females) aged 2–4 years and weighing 32.5–39.7 kg. After jugular vein catheterization, dogs were administered a single oral or IV dose of amitriptyline...
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