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Major depressive disorder (MDD) is associated with excessive self-focus and a tendency to engage in self-reflection. Women are more inclined to form negative thoughts when facing problems such as social rejection. The neuroimaging studies addressing MDD females are still rare. The medial prefrontal cortex, a central node of anterior default mode network (DMN), plays an important role in the pathophysiology...
Women are at a twofold higher risk of developing major depressive disorder (MDD) than that of men. However, the investigation of female MDD patients functional brain activity is rare and the detailed mechanism remains unclear. The present work is to explore the altered spontaneous neural activity measured with regional homogeneity (ReHo) in female MDD patients using resting-state functional magnetic...
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