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We studied the neurophysiology of neurons from the central nervous system (CNS) of rats that were exposed to a long-term (3–4 weeks) low oxygen (FiO 2 = 9.5 ± 0.5%) environment (exposed). Age-matched normoxic animals served as controls (naive). We measured membrane potential (V m ) and input resistance (R m ) at rest and in response to two levels (20% and 0% O 2 ) of...
Intracellular electrophysiologic recordings were performed in brain slices from adult rats to compare the response of brain stem hypoglossal neurons (XII) and layer II/III neocortical neurons (NCX) to two levels of oxygen deprivation (hypoxia, pO 2 = 15-20 Torr; anoxia, pO 2 = 0 Torr). These recordings were also used during re-oxygenation after hypoxia or anoxia to study neuronal...
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