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Background
The risk of occult gastrointestinal bleeding (OGIB) is known to be increased among human dialysis patients suffering from end‐stage renal disease. However, there are no studies to date that investigate the incidence of OGIB in either dogs or people with chronic kidney disease (CKD), irrespective of dialysis.
Objectives
The purpose of the study was to determine whether the incidence of...
Friedreich ataxia is the consequence of frataxin deficiency, most often caused by a GAA repeat expansion in intron 1 of the corresponding gene. Frataxin is a mitochondrial protein involved in iron homeostasis. As an attempt to generate a mouse model of the disease, we introduced a (GAA) 230 repeat within the mouse frataxin gene by homologous recombination. GAA repeat knockin mice...
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