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Background
Vaccination with Bacillus Calmette‐Guérin (BCG) is used in many countries as protection against tuberculosis. Studies have suggested that BCG may also have non‐specific effects, reducing non‐tuberculosis mortality, morbidity, and atopic manifestations. In this study, we evaluated the effect of neonatal BCG vaccination on allergic sensitization and suspected food allergy at 13 months of...
The heterologous or non-specific effects (NSEs) of vaccines, at times defined as “off-target effects” suggest that they can affect the immune response to organisms other than their pathogen-specific intended purpose. These NSEs have been the subject of clinical, immunological and epidemiological studies and are increasingly recognized as an important biological process by a growing group of immunologists...
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