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So far, no data is available on the role of the tumor stem cell marker doublecortin-like kinase 1 (DCLK1) in head and neck squamous cell carcinoma (HNSCC). The purpose of this study was to evaluate DCLK1 expression in HNSCC patients that underwent surgery and postoperative radiotherapy, and to assess its potential as a therapeutic target in vitro.We immunohistochemically stained for DCLK1 in 127 sections...
To retrospectively analyse a large consecutive cohort of patients with anal cancer for treatment-related factors influencing local control and survival.All patients referred for primary radiotherapy at Medical University of Vienna in 1990–2002 with anal canal carcinoma without distant metastases were analysed. Treatment consisted of external radiotherapy with or without brachytherapy and with or without...
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