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AimThe nontoxic mutant of diphtheria toxin (DT) has been demonstrated to act as a receptor‐specific carrier protein to delivery drug into brain. Recent research showed that the truncated “receptorless” DT was still capable of being internalized into cells. This study investigated the effects and potential mechanisms of DT270‐326, a truncated “receptorless” DT, on the permeability of the blood–tumor...
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