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Biocomfortable polyethylenimine (PEI) coated Fe3O4 nanoparticles (NPs) have been successfully fabricated for their magnetic hyperthermia performance. After coating with PEI, the sample reveals a tiptop performance of magnetic property and an enhanced biocompatibility. Compared with Fe3O4 NPs, PEI-coated Fe3O4 NPs do not induce notable cell cytotoxic effect at their higher concentration, which indicates...
The effective delivery of therapeutic agent to target tissue is a central challenge in drug delivery. Therefore, externally stimuli controlled drug release has emerged as a promising method to localized delivery. In addition, the design of a suitable drug loaded nanocarrier to target lesion and response to a certain stimulus is also a main issue. In this study, we fabricate superparamagnetic iron...
Owing to the limitations of the conventional flexible endoscopes used in gastrointestinal diagnostic procedures, which cause discomfort and pain in patients, a wireless capsule endoscope has been developed and commercialized. Despite the many advantages of the wireless capsule endoscope, its restricted mobility has limited its use to diagnosis of the esophagus and small intestine only. Therefore,...
Recently, a conventional capsule endoscope was developed and has been used for a diagnosis to make up for the limitations of conventional flexible endoscopy. However, the capsule endoscope has also some limitations and low diagnostic effectiveness because of its passive movement through the peristaltic motion of digestive organs. To overcome these problems, there are several researches about active...
In this paper, we proposed an intravascular therapeutic microrobot using an electromagnetic actuation (EMA) system with bi-plane X-ray imaging device. The proposed EMA system consists of Helmholtz-Maxwell coils, uniform-gradient saddle coils. The Helmholtz-Maxwell coils are located along y-axis, and uniform-gradient saddle coils are located perpendicular to y-axis. In order to align the microrobot...
For the actuation of mini-robots, electromagnetic based actuation (EMA) methods were proposed. EMA system has many advantages for the wireless actuation of mini-robots. This paper introduces our proposed biomimetic swimming mini-robots such as tadpole robot and jellyfish robot. The biomimetic swimming mini-robots could be driven by an external alternating magnet field using three pairs of Helmholtz...
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