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Background
Poor nutrition during fetal development programs postnatal kidney function. Understanding postnatal consequences in nonhuman primates (NHP) is important for translation to our understanding the impact on human kidney function and disease risk. We hypothesized that intrauterine growth restriction (IUGR) in NHP persists postnatally, with potential molecular mechanisms revealed by Western‐type...
Background
Little is known about the repertoire of non‐human primate kidney genes expressed throughout development. The present work establishes an understanding of the primate renal transcriptome during fetal development in the context of renal maturation.
Methods
The baboon kidney transcriptome was characterized at 60‐day gestation (DG), 90 DG, 125 DG, 140 DG, 160 DG and adulthood (6‐12 years)...
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