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In a focused exploration, thiazolidin‐4‐ones with different C‐2 and N‐3 substituent groups were synthesized and evaluated as non‐nucleoside reverse transcriptase inhibitors against HIV‐1. This has led to new active compounds sporting heteroaryls at both C‐2 and N‐3 positions prompting to view them in the backdrop of nevirapine. To assign the molecular attributes for the activity, the compounds are...
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