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Aims
No reports examine the relationship between in‐utero exposure to gestational diabetes mellitus (GDM), offspring epigenetic age acceleration (EAA), and offspring insulin sensitivity.
Methods
Using data from a cohort study, we examined associations between GDM in‐utero exposure and offspring EAA at approximately 10 years of age, using separate regression models adjusting for offspring chronological...
Perturbations in early life environments, including intrauterine exposure to maternal gestational diabetes (GDM), are hypothesized to lead to metabolic imprinting resulting in increased risk of cardiometabolic outcomes later in life. We aimed to 1) identify candidate genes and biological pathways associated with differentially methylated regions (DMRs) in relation to exposure to GDM in utero and,...
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