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Women with genetic hypercholesterolemias, including familial hypercholesterolemia (FH), are at greatly increased lifetime risk of cardiovascular disease. All women with low-density lipoprotein cholesterol (LDL-C) ≥190 mg/dL after a trial of lifestyle therapy should receive statin therapy. Aggressive risk factor control and complete avoidance of tobacco exposure are required in order to minimize the...
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