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10-Hydroxy-trans-2-decenoic acid (10-HDA) is a major medium chain fatty acid in royal jelly. In this study, the rat vascular smooth muscle cells (VSMCs) were pretreated with 10-HDA (250 μM, 500 μM, 1000 μM), followed by incubation with Angiotensin II (Ang II, 100 nM). 10-HDA significantly reduced the productions of Ang II induced inflammatory cytokines interleukin 6 and C-reactive protein, through...
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