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Background
Long‐term opioid therapy for chronic pain management requires regularly assessing and documenting benefits and side effects. Opioid‐induced sex hormone disturbances are a complication that needs to be assessed routinely and perhaps not only when suspected. There is abundant literature about its prevalence, clinical consequences, and treatment, yet routine hormone screening and appropriate...
Background
There are interrelationships between the autonomic nervous system and pain. This study aims to explore the effect of different autonomic manipulations on pain perception and modulation.
Methods
Twenty healthy subjects (10 men and 10 women, mean age 25 ± 3 years) participated in this single‐blinded, semi‐randomized, controlled study, which included 2 study visits. Warm detection thresholds,...
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