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Aims/hypothesis Adaptation to energy restriction is associated with changes in gene expression in adipose tissue. However, it is unknown to what extent these changes are dependent on the energy restriction as such or on the macronutrient composition of the diet. Methods We determined the levels of transcripts for 38 genes that are expressed in adipose tissue and encode transcription factors, enzymes,...
We wanted to assess the effect of rapid diet-induced weight loss on the function of obese, knee osteoarthritis (OA) patients.Eighty patients with knee OA, 89% women (n=71), were recruited. Mean (SD) body-mass index (BMI) was 35.9 (5.1) kg/m 2 and age 62.6 (11.1) years. Patients were randomized to either a low-energy diet (LED 3.4MJ/day), or a control diet (5MJ/day). The LED group had weekly...
In nutritional research, the sensations of appetite have mostly been studied as a physiological phenomenon. However, in order to understand the significance of appetite for everyday eating habits, it is pertinent to include the social dimension. In a qualitative interview study, using qualitative semi-structured in-depth interviews, we investigated how appetite was experienced and handled in the context...
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