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Effects of ethanol on brain development and heat shock protein 70 (HSP70) expression were investigated in mouse embryos using the whole embryo culture, mid-brain culture, and streptavidin-biotin peroxidase complex (SABC) method. In the whole embryo culture, ethanol (1, 2 and 4 mg/ml) inhibited brain development dose dependently and the most prevalent abnormality was the open cephalic neural tube....
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