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The high mobility group (HMG)‐box is a DNA‐binding domain characteristic of various eukaryotic DNA‐binding proteins. 3xHMG‐box proteins (containing three copies of the HMG‐box domain and a unique basic N‐terminal domain) are specific for plants and the Arabidopsis genome encodes two versions termed 3xHMG‐box1 and 3xHMG‐box2, whose expression is cell cycle‐dependent, peaking during mitosis.
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